Microtubule-cyclodextrin conjugate: Functionalization of motile filament with molecular inclusion ability

被引:18
作者
Kato, KA
Goto, R
Katoh, K
Shibakami, M
机构
[1] Natl Inst Adv Ind Sci & Technol, AIST, Inst Biol Resources & Funct, Tsukuba, Ibaraki 3058565, Japan
[2] Natl Inst Adv Ind Sci & Technol, AIST, Neurosci Res Inst, Tsukuba, Ibaraki 3058568, Japan
关键词
microtubule; cyclodextrin; inclusion ability; motility assay; chemical modification;
D O I
10.1271/bbb.69.646
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
A microtubule-beta-cyclodextrin conjugate was prepared on a kinesin-adsorbed glass surface by chemical and biochemical means. Fluorescence microscope observation and a motility assay indicated that the conjugate simultaneously expressed an inherent motor function and an inclusion property.
引用
收藏
页码:646 / 648
页数:3
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