The tomato as a functional food

被引:247
作者
Canene-Adams, K
Campbell, JK
Zaripheh, S
Jeffery, EH
Erdman, JW [1 ]
机构
[1] Univ Illinois, Dept Food Sci & Human Nutr, Urbana, IL 61801 USA
[2] Univ Illinois, Div Nutr Sci, Urbana, IL 61801 USA
关键词
tomato; lycopene; prostate cancer; cardiovascular disease;
D O I
10.1093/jn/135.5.1226
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
Tomatoes are the fourth most commonly consumed fresh vegetable and the most frequently consumed canned vegetable in the American diet. There is emerging epidemiology data supporting the connection between increased tomato consumption and reduced risk for both cardiovascular disease and prostate cancer. Here we will summarize the nutrient and the phytochemical content of tomatoes and tomato products, and how these bioactive components might act together to modulate disease development. Recent animal studies have investigated tomatoes, lycopene, and prostate cancer using the N-methyl-N-nitrosourea and Dunning rat models. These animal studies also suggest that diets containing tomatoes may decrease the risk or the progression of prostate cancer. Due to the frequency and the extent of tomato consumption, the supporting epidemiological and animal data, which connect increased intakes with decreased cancer and cardiovascular disease risk, tomato's role in the American diet is of undeniable importance as part of a healthy diet.
引用
收藏
页码:1226 / 1230
页数:5
相关论文
共 39 条
  • [1] *ACS, 2005, CANC FACTS FIG
  • [2] *AGR STAT, 2003, STAT VEGETABLES MELO
  • [3] Beecher GR, 1998, P SOC EXP BIOL MED, V218, P98, DOI 10.3181/00379727-218-44282a
  • [4] Prostate carcinogenesis in N-methyl-N-nitrosourea (NMU)-testosterone-treated rats fed tomato powder, lycopene, or energy-restricted diets
    Boileau, TWM
    Liao, ZM
    Kim, S
    Lemeshow, S
    Erdman, JW
    Clinton, SK
    [J]. JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2003, 95 (21): : 1578 - 1586
  • [5] ADENOCARCINOMAS OF THE PROSTATE INDUCED BY N-NITROSO-N-METHYLUREA IN RATS PRETREATED WITH CYPROTERONE-ACETATE AND TESTOSTERONE
    BOSLAND, MC
    PRINSEN, MK
    KROES, R
    [J]. CANCER LETTERS, 1983, 18 (01) : 69 - 78
  • [6] BOSLAND MC, 1992, J CELL BIOCHEM, P89
  • [7] Canene-Adams K, 2004, FASEB J, V18, pA886
  • [8] Oxidative DNA damage in prostate cancer patients consuming tomato sauce-based entrees as a whole-food intervention
    Chen, LW
    Stacewicz-Sapuntzakis, M
    Duncan, C
    Sharifi, R
    Ghosh, L
    van Breemen, R
    Ashton, D
    Bowen, PE
    [J]. JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2001, 93 (24): : 1872 - 1879
  • [9] Cohen LA, 2002, ANN NY ACAD SCI, V963, P148
  • [10] THE SINGLET OXYGEN AND CAROTENOID INTERACTION
    CONN, PF
    SCHALCH, W
    TRUSCOTT, TG
    [J]. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY, 1991, 11 (01) : 41 - 47