Ultrasonic and viscoelastic properties of skin under transverse mechanical stress in vitro

被引:92
作者
Pan, L [1 ]
Zan, L [1 ]
Foster, FS [1 ]
机构
[1] Univ Toronto, Sunnybrook Hlth Sci Ctr, Dept Med Biophys, Toronto, ON M4N 3M5, Canada
基金
英国医学研究理事会;
关键词
ultrasound; skin; frequency-dependent attenuation; frequency-dependent backscatter; speed of sound; stress relaxation; creep; Young's modulus; viscoelasticity;
D O I
10.1016/S0301-5629(98)00071-4
中图分类号
O42 [声学];
学科分类号
070206 ; 082403 ;
摘要
Ultrasound properties of rabbit and human skin tissues under transverse stress have been studied in vitro over the frequency range from 15 MHz to 40 MHz. B-scan images show significant increases in average dermal grey-scale levels for increasing strain. Quantitative measurements show that ultrasound attenuation coefficients decrease significantly with increasing strain. A linear decrease of 0.109 dB/mm/strain % in rabbit skin and 0.069 dB/mm/strain% in human breast reduction skin was observed at 30 MHz, Experimental results show that backscattering coefficients only exhibit minor variation with strain. The speed of sound in human skin appears to be age-dependent, The viscoelastic and mechanical properties of skin, including stress relaxation, creep and Young's modulus as a function of strain were also studied. (C) 1998 World Federation for Ultrasound in Medicine & Biology.
引用
收藏
页码:995 / 1007
页数:13
相关论文
共 39 条
[1]   ACOUSTIC COUPLING FROM A FOCUSED TRANSDUCER TO A FLAT PLATE AND BACK TO THE TRANSDUCER [J].
CHEN, XC ;
SCHWARZ, KQ ;
PARKER, KJ .
JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA, 1994, 95 (06) :3049-3054
[2]   FREQUENCY-DEPENDENCE OF ULTRASOUND ATTENUATION AND BACKSCATTER IN BREAST-TISSUE [J].
DASTOUS, FT ;
FOSTER, FS .
ULTRASOUND IN MEDICINE AND BIOLOGY, 1986, 12 (10) :795-808
[3]  
Di Nardo A, 1992, Exp Dermatol, V1, P121
[4]  
Fornage B D, 1993, Radiol Med, V85, P149
[5]  
Fornage B D, 1995, Clin Diagn Ultrasound, V30, P85
[6]   IMAGING OF THE SKIN WITH 20-MHZ US [J].
FORNAGE, BD ;
MCGAVRAN, MH ;
DUVIC, M ;
WALDRON, CA .
RADIOLOGY, 1993, 189 (01) :69-76
[7]   THE ULTRASOUND MACROSCOPE - INITIAL STUDIES OF BREAST-TISSUE [J].
FOSTER, FS ;
STRBAN, M ;
AUSTIN, G .
ULTRASONIC IMAGING, 1984, 6 (03) :243-261
[8]   PRINCIPLES AND APPLICATIONS OF ULTRASOUND BACKSCATTER MICROSCOPY [J].
FOSTER, FS ;
PAVLIN, CJ ;
LOCKWOOD, GR ;
RYAN, LK ;
HARASIEWICZ, KA ;
BERUBE, L ;
RAUTH, AM .
IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL, 1993, 40 (05) :608-617
[9]  
Fung Y.C., 1993, BIOMECHANICS MECH PR, P41
[10]  
GASSENMAIER G, 1992, ULTRASOUND DERMATOLO, P221