Interfacial tension of the two-component bilayer lipid membrane modelling of cell membrane

被引：42

作者：

Petelska, AD

Figaszewski, ZA

机构：

[1] Warsaw Univ, Fac Chem, Lab Interfacial Electrochem, PL-02093 Warsaw, Poland

[2] Univ Bialystok, Inst Chem, PL-15443 Bialystok, Poland

来源：

BIOELECTROCHEMISTRY AND BIOENERGETICS | 1998年 / 46卷 / 02期

关键词：

interfacial tension; bilayer lipid membrane; the two-component bilayer lipid membrane; lecithin; cholesterol;

D O I：

10.1016/S0302-4598(98)00138-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Interfacial tension has been determined for two-component lipid membranes. The measurement of the interfacial tension consisted in applying a pressure difference on both sides of the membrane and the measuring of its curvature. Lecithin and cholesterol were used because of their presence in biological membranes. Interfacial tension values of pure components are 1.623 mN/m and 4.715 mN/m. The 1:1 complex was formed during formation of lecithin/cholesterol lipid membrane. The following parameters describing the complex were determined: Gamma(3) the surface concentration of the lipid membrane formed of lecithin/cholesterol complex, gamma(3), the interfacial tension of such membrane, and the stability constant of the complex, K. These values are 3.900 x 10(-7) mol/m(2), 4.423 mN/m (mean) and 2.661 x 10(7), respectively. (C) 1998 Elsevier Science S.A. All rights reserved.

引用

页码：199 / 204

页数：6

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