iPath2.0: interactive pathway explorer

被引：216

作者：

Yamada, Takuji ^{[1
]}

Letunic, Ivica ^{[1
]}

Okuda, Shujiro ^{[2
]}

Kanehisa, Minoru ^{[3
]}

Bork, Peer ^{[1
]}

机构：

[1] EMBL, D-69117 Heidelberg, Germany

[2] Ritsumeikan Univ, Coll Life Sci, Dept Bioinformat, Shiga 5258577, Japan

[3] Kyoto Univ, Inst Chem Res, Bioinformat Ctr, Kyoto 6110011, Japan

来源：

NUCLEIC ACIDS RESEARCH | 2011年 / 39卷

关键词：

METABOLIC PATHWAYS; KEGG ATLAS; NETWORKS; METAGENOMICS; ANNOTATION; DATABASE; GENOME; TOOL;

D O I：

10.1093/nar/gkr313

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

iPath2.0 is a web-based tool (http://pathways.embl.de) for the visualization and analysis of cellular pathways. Its primary map summarizes the metabolism in biological systems as annotated to date. Nodes in the map correspond to various chemical compounds and edges represent series of enzymatic reactions. In two other maps, iPath2.0 provides an overview of secondary metabolite biosynthesis and a hand-picked selection of important regulatory pathways and other functional modules, allowing a more general overview of protein functions in a genome or metagenome. iPath2.0's main interface is an interactive Flash-based viewer, which allows users to easily navigate and explore the complex pathway maps. In addition to the default pre-computed overview maps, iPath offers several data mapping tools. Users can upload various types of data and completely customize all nodes and edges of iPath2.0's maps. These customized maps give users an intuitive overview of their own data, guiding the analysis of various genomics and metagenomics projects.

引用

页码：W412 / W415

页数：4

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