Efficient methylation of carboxylic acids with potassium hydroxide/methyl sulfoxide and iodomethane

被引：29

作者：

Avila-Zárraga, JG

Martínez, R

机构：

[1] Univ Nacl Autonoma Mexico, Fac Quim, Dept Organ, Coyoacan 04510, DF, Mexico

[2] Univ Nacl Autonoma Mexico, Inst Quim, Coyoacan 04510, DF, Mexico

来源：

SYNTHETIC COMMUNICATIONS | 2001年 / 31卷 / 14期

关键词：

D O I：

10.1081/SCC-100104469

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Methylation of several carboxylic acids was promoted by potassium hydroxide in methyl sulfoxide and iodomethane to produce corresponding methyl esters in good yield. This method has advantage over other described methods because it uses inexpensive reagents and the reaction is carried out under mild and favorable conditions.

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收藏

页码：2177 / 2183

页数：7

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