The Relationship Between Patient-Reported Tolerability Issues With Oral Antidiabetic Agents and Work Productivity Among Patients Having Type 2 Diabetes

被引：14

作者：

DiBonaventura, Marco ^{[1
]}

Link, Charles ^{[2
]}

Pollack, Michael F. ^{[3
]}

Wagner, Jan-Samuel ^{[1
]}

Williams, Setareh A. ^{[3
]}

机构：

[1] Kantar Hlth, New York, NY USA

[2] Univ Delaware, Newark, DE USA

[3] AstraZeneca, Wilmington, DE USA

来源：

JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE | 2011年 / 53卷 / 02期

关键词：

TREATMENT SATISFACTION; ADVERSE EVENTS; THERAPY; ASSOCIATION; DISABILITY; ADHERENCE; VALIDITY; HEALTH; IMPACT;

D O I：

10.1097/JOM.0b013e318209e0ce

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Objective: To investigate the association between reported oral antidiabetic tolerability issues and work productivity, activity impairment, and indirect costs. Methods: Data were collected from the 2006 to 2008 US National Health and Wellness Survey and the Lightspeed Research, using an Internet-based questionnaire (N = 2074). Results: Absenteeism, presenteeism, overall work impairment, and activity impairment increased as the number of tolerability issues increased. Similar results were observed using a diabetes-specific productively measure. Total annual adjusted indirect costs (absenteeism and presenteeism costs summed) were $2759, $5533, $7537, and $8405 for patients with 1, 2, 3, and 4 or more tolerability issues, respectively. Conclusions: The consideration of tolerability profiles of oral antidiabetic agents may lead to improved productivity among treated patients. Furthermore, targeted educational programs regarding risks and management of these issues to employees with type 2 diabetes mellitus may benefit both employers and patients.

引用

页码：204 / 210

页数：7

共 21 条

[1] Standards of Medical Care in Diabetes-2009
不详
[J]. DIABETES CARE, 2009, 32 : S13 - S61
[2] Association between oral antidiabetic use, adverse events and outcomes in patients with type 2 diabetes
Asche, C. V.
McAdam-Marx, C.
Shane-McWhorter, L.
Sheng, X.
Plauschinat, C. A.
[J]. DIABETES OBESITY & METABOLISM, 2008, 10 (08) : 638 - 645
[3] Evaluation of adverse events of oral antihyperglycaemic monotherapy experienced by a geriatric population in a real-world setting - A retrospective cohort analysis
Asche, Carl V.
McAdam-Marx, Carrie
Shane-McWhorter, Laura
Sheng, Xiaoming
Plauschinat, Craig A.
[J]. DRUGS & AGING, 2008, 25 (07) : 611 - 622
[4] ASCHE CV, 2006, AM SOC HLTH SYST PHA
[5] Association of insomnia with quality of life, work productivity, and activity impairment
Bolge, Susan C.
Doan, Justin F.
Kannan, Hema
Baran, Robert W.
[J]. QUALITY OF LIFE RESEARCH, 2009, 18 (04) : 415 - 422
[6] Measuring the impact of diabetes through patient report of treatment satisfaction, productivity and symptom experience
Brod, M
Skovlund, SE
Wittrup-Jensen, KU
[J]. QUALITY OF LIFE RESEARCH, 2006, 15 (03) : 481 - 491
[7] A NEW METHOD OF CLASSIFYING PROGNOSTIC CO-MORBIDITY IN LONGITUDINAL-STUDIES - DEVELOPMENT AND VALIDATION
CHARLSON, ME
POMPEI, P
ALES, KL
MACKENZIE, CR
[J]. JOURNAL OF CHRONIC DISEASES, 1987, 40 (05): : 373 - 383
[8] Health, absence, disability, and presenteeism cost estimates of certain physical and mental health conditions affecting US employers
Goetzel, RZ
Long, SR
Ozminkowski, RJ
Hawkins, K
Wang, SH
Lynch, W
[J]. JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE, 2004, 46 (04) : 398 - 412
[9] Oral antihyperglycemic therapy for type 2 diabetes - Scientific review
Inzucchi, SE
[J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2002, 287 (03): : 360 - 372
[10] Clinical pearls and strategies to optimize patient outcomes
Joy, Scott V.
[J]. DIABETES EDUCATOR, 2008, 34 : 54S - 59S

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