The effect of local application of mitomycin-C on the development of capsule around silicone implants in the breast: An experimental study in mice

被引：34

作者：

Frangou, J

Kanellaki, M

机构：

[1] Thessaloniki,

[2] Greece,undefined

来源：

AESTHETIC PLASTIC SURGERY | 2001年 / 25卷 / 02期

关键词：

breast implant; capsural contracture; mitomycin-C;

D O I：

10.1007/s002660010108

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

In this experimental study on mice we try to prove that capsule formation around breast implants is considerably diminished after topical application of Mitomycin-C (MMC). MMC solution is applied under the breast tissue or pectoralis major muscle, in the pocket of the silicone implant and just before placing it. This is a morphological study of the connective tissue formed around the implant, under light and electron microscope. Our results suggest that it is worthwhile working on a clinical study trying to prevent the most common complication of breast implants, contracture of a capsule.

引用

页码：118 / 128

页数：11

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