Rab proteins as membrane organizers

被引：2656

作者：

Zerial, M ^{[1
]}

McBride, H ^{[1
]}

机构：

[1] EMBL, Max Planck Inst Mol Cell Biol & Genet, D-69117 Heidelberg, Germany

来源：

NATURE REVIEWS MOLECULAR CELL BIOLOGY | 2001年 / 2卷 / 02期

关键词：

D O I：

10.1038/35052055

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Cellular organelles in the exocytic and endocytic pathways have a distinctive spatial distribution and communicate through an elaborate system of vesiculo-tubular transport. Rab proteins and their effectors coordinate consecutive stages of transport, such as vesicle formation, vesicle and organelle motility, and tethering of vesicles to their target compartment. These molecules are highly compartmentalized in organelle membranes, making them excellent candidates for determining transport specificity and organelle identity.

引用

页码：107 / 117

页数：11

共 106 条

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