The choreographed dynamics of bacterial chromosomes

被引:39
作者
Gitai, Z [1 ]
Thanbichler, M
Shapiro, L
机构
[1] Stanford Univ, Sch Med, Beckman Ctr, Dept Dev Biol, Stanford, CA 94305 USA
[2] Princeton Univ, Dept Mol Biol, Princeton, NJ 08544 USA
关键词
D O I
10.1016/j.tim.2005.03.006
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Despite decades of study, the exquisite temporal and spatial organization of bacterial chromosomes has only recently been appreciated. The direct visualization of specific chromosomal loci has revealed that bacteria condense, move and position their chromosomes in a reproducible fashion. The realization that bacterial chromosomes are actively translocated through the cell suggests the existence of specific mechanisms that direct this process. Here, we review bacterial chromosome dynamics and our understanding of the mechanisms that direct and coordinate them.
引用
收藏
页码:221 / 228
页数:8
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