Characterization of allergens in plant-derived spices: Apiaceae spices, pepper (Piperaceae), and paprika (bell peppers, Solanaceae)

被引:25
作者
Ebner, C [1 ]
Jensen-Jarolim, E [1 ]
Leitner, A [1 ]
Breiteneder, H [1 ]
机构
[1] Univ Vienna, Inst Gen & Expt Pathol, A-1090 Vienna, Austria
关键词
D O I
10.1111/j.1398-9995.1998.tb04961.x
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
Allergens in spices from the botanic families Apiaceae, Piperaceae, and Solanaceae were characterized. IgE-immunoblotting and IgE-inhibition experiments revealed broad cross-reactivity among spices and to pollen-derived proteins. Moreover, monoclonal antibodies raised against cross-reactive pollen allergens (profilin, Bet v 1) detected homologous proteins in almost every spice source analyzed. It can be concluded that allergy to spices rarely represents an autonomous sensitization, but is rather a consequence of pollen allergy on the basis of immunologic cross-reactivity. (C) Munksgaard 1998.
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收藏
页码:52 / 54
页数:3
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