Controlling gene expression in transgenics

被引:50
作者
Gallie, DR [1 ]
机构
[1] Univ Calif Riverside, Dept Biochem, Riverside, CA 92521 USA
关键词
D O I
10.1016/S1369-5266(98)80020-4
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
The repertoire of cis-regulatory elements has increased to a level of sophistication that offers considerable spatial and temporal control over transgene expression. Recent advances made with transgenes have revealed that the control of their expression is also influenced by factors that range from transgene copy number and arrangement to nuclear architecture and chromosomal location. These factors must now be included with the standard considerations of transcriptional and translational enhancers of gene expression during transgene design.
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收藏
页码:166 / 172
页数:7
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