Organometallic nucleophilic ring-opening of endo peroxides

被引：18

作者：

Schwaebe, MK ^{[1
]}

Little, RD ^{[1
]}

机构：

[1] UNIV CALIF SANTA BARBARA,DEPT CHEM,SANTA BARBARA,CA 93106

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 37期

关键词：

D O I：

10.1016/S0040-4039(96)01494-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reaction of symmetrical and unsymmetrical endo peroxides with organometallic reagents affords hydroxy ethers. Primary, secondary, vinyl and aryl groups can be transferred with alkyllithium and Grignard reagents providing the best yields, organozincates, moderate. This demonstrates a new reactivity pattern for endoperoxides and provides a novel method for the formation of a variety of useful building blocks. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：6635 / 6638

页数：4

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