Synthesis and antibacterial activity of cyclic imides: 3,4-dichloromaleimides and 3-chloro-4-substituted-maleimides

被引：28

作者：

Andricopulo, AD ^{[1
]}

Yunes, RA

Nunes, RJ

Savi, AOS

Correa, R

Cruz, AB

Cechinel, V

机构：

[1] Univ Fed Santa Catarina, Dept Quim, BR-88040900 Florianopolis, SC, Brazil

[2] Univ Vale Itajai, FAQFAR, NIQFAR, UNIVALI, BR-88302202 Itajai, SC, Brazil

来源：

QUIMICA NOVA | 1998年 / 21卷 / 05期

关键词：

cyclic imides; antibacterial activity; cyclic imido double bond;

D O I：

10.1590/S0100-40421998000500008

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In the present study, new N-aryl and N-alkylarylcyclic imides were synthesized and their antibacterial properties against Escherichia coli and Staphylococcus aureus were evaluated by using the diffusion method, All compounds were obtained in good yield (54 - 95%) and characterized by spectral data (H-1-NMR, MS, IR) and elemental analysis (CHN), The biological results indicated that some compounds exert significative antibacterial effects, confirming previous studies on biological activities of cyclic imides.

引用

页码：573 / 577

页数：5