Microfluid mechanics: progress and opportunities

被引:73
作者
Giordano, N [1 ]
Cheng, JT [1 ]
机构
[1] Purdue Univ, Dept Phys, W Lafayette, IN 47907 USA
关键词
D O I
10.1088/0953-8984/13/15/201
中图分类号
O469 [凝聚态物理学];
学科分类号
070205 ;
摘要
The application of microfabrication techniques to problems involving fluids is reviewed. A number of scientific issues have been addressed using microstructures designed to confine and manipulate fluids. These problems include studies of fluid motion in percolative structures. chemical applications involving small volumes of reactants and products, biologically inspired experiments involving the manipulation of individual molecules, and studies of fundamental properties of liquids in extremely small geometries. Representative work is described, slang with the ingenious fabrication methods which have been developed. We believe that there are many opportunities for interesting basic physics and also interdisciplinary work in this area. The primary goal of this article is to bring this message to the general physics community.
引用
收藏
页码:R271 / R295
页数:25
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共 88 条
  • [1] AUSTIN RH, 1993, ANALUSIS, V21, P235
  • [2] Biotechnology at low Reynolds numbers
    Brody, JP
    Yager, P
    Goldstein, RE
    Austin, RH
    [J]. BIOPHYSICAL JOURNAL, 1996, 71 (06) : 3430 - 3441
  • [3] THE DRAINAGE OF THIN LIQUID-FILMS BETWEEN SOLID-SURFACES
    CHAN, DYC
    HORN, RG
    [J]. JOURNAL OF CHEMICAL PHYSICS, 1985, 83 (10) : 5311 - 5324
  • [4] EXPERIMENTAL-STUDY OF TRACER DISPERSION IN FLOW THROUGH TWO-DIMENSIONAL NETWORKS OF ETCHED CAPILLARIES
    CHARLAIX, E
    HULIN, JP
    LEROY, C
    ZARCONE, C
    [J]. JOURNAL OF PHYSICS D-APPLIED PHYSICS, 1988, 21 (12) : 1727 - 1732
  • [5] SOME MECHANISMS OF IMMISCIBLE FLUID DISPLACEMENT IN SMALL NETWORKS
    CHEN, JD
    [J]. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 1986, 110 (02) : 488 - 503
  • [6] CHENG JT, 2001, THESIS PURDUE U W LA
  • [7] CHENG JT, 2001, IN PRESS
  • [8] Microchip-based capillary electrophoresis for immunoassays: Analysis of monoclonal antibodies and theophylline
    Chiem, N
    Harrison, DJ
    [J]. ANALYTICAL CHEMISTRY, 1997, 69 (03) : 373 - 378
  • [9] Patterned deposition of cells and proteins onto surfaces by using three-dimensional microfluidic systems
    Chiu, DT
    Jeon, NL
    Huang, S
    Kane, RS
    Wargo, CJ
    Choi, IS
    Ingber, DE
    Whitesides, GM
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (06) : 2408 - 2413
  • [10] Sorting by diffusion: An asymmetric obstacle course for continuous molecular separation
    Chou, CF
    Bakajin, O
    Turner, SWP
    Duke, TAJ
    Chan, SS
    Cox, EC
    Craighead, HG
    Austin, RH
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (24) : 13762 - 13765