Proteomic diagnosis of Sjoren's syndrome

被引：42

作者：

Giusti, Laura ^{[1
,2
,3
]}

Baldini, Chiara ^{[1
,2
,3
]}

Bazzichi, Laura ^{[1
,2
,3
]}

Bombardieri, Stefano ^{[1
,2
,3
]}

Lucocchini, Antonio ^{[1
,2
,3
]}

机构：

[1] Univ Pisa, Dept Psychiat, I-56126 Pisa, Italy

[2] Univ Pisa, Dept Neurobiol, I-56126 Pisa, Italy

[3] Univ Pisa, Dept Pharmacol & Biotechnol, I-56126 Pisa, Italy

来源：

EXPERT REVIEW OF PROTEOMICS | 2007年 / 4卷 / 06期

关键词：

D O I：

10.1586/14789450.4.6.757

中图分类号：

Q5 [生物化学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

In the last few years, a growing interest has arisen in the application of proteomic analysis to rheumatic disease. Sjogren's syndrome is a systemic disease that affects exocrine glands directly, and is therefore expected to influence the composition of the whole human saliva and lachrymal fluid. Therefore, a rising number of studies have been performed in an attempt to characterize the salivary and lachrymal protein profiles of patients with Sjogren's syndrome by using a proteomic approach. This review summarizes the state of the art and the potential application of proteomics in the systematic search for diagnostic biomarkers in Sjogren's syndrome.

引用

页码：757 / 767

页数：11

共 89 条

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