Macrophage receptors implicated in the "adaptive" form of innate immunity

被引：108

作者：

Bowdish, D. M. E. ^{[1
]}

Loffredo, M. S. ^{[1
]}

Mukhopadhyay, S. ^{[1
]}

Mantovani, Alberto ^{[2
]}

Gordon, S. ^{[1
]}

机构：

[1] Univ Oxford, Sir William Dunn Sch Pathol, Oxford OX1 3RE, England

[2] Ist Clin Humanitas, Res Lab Immunol & Inflammat, I-20089 Milan, Italy

来源：

MICROBES AND INFECTION | 2007年 / 9卷 / 14-15期

基金：

英国惠康基金;

关键词：

macrophages; innate immunity; scavenger receptors; dectin-1; pentraxin;

D O I：

10.1016/j.micinf.2007.09.002

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The adaptive component of innate immunity occurs during the course of infection when antigen presenting cells alter expression of soluble or surface associated pattern recognition receptors. This results in increased recognition of a broad spectrum of pathogens, enhancement of effector functions and altered regulation of the inflammatory response. (c) 2007 Elsevier Masson SAS. All rights reserved.

引用

页码：1680 / 1687

页数：8

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