Vitiligo

被引：261

作者：

Kovacs, SO ^{[1
]}

机构：

[1] Barnes Hosp, Dept Dermatol, St Louis, MO 63110 USA

来源：

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY | 1998年 / 38卷 / 05期

关键词：

D O I：

10.1016/S0190-9622(98)70194-X

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

The destruction of melanocytes is the cause of depigmented maculae that clinically represent the disease vitiligo. Although the cause is unknown, various theories such as the autoimmune, autocytotoxic, and neural hypotheses have been proposed. Extensive research has provided numerous answers regarding the pathogenesis, histopathologic evidence, and treatment of vitiligo. This discussion of vitiligo summarizes the varied clinical presentations of the disease, theories attempting to explain the mechanism of melanocyte destruction, histopathologic findings, and different treatment modalities currently available.

引用

页码：647 / 666

页数：20

共 295 条

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[2]

ABDELNASER MB, 1991, J INVEST DERMATOL, V96, P1024

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