Pancreatic endocrine cells in Bufo bufo:: immunocytochemistry and ultrastructure

被引:11
作者
Accordi, F [1 ]
Bracci, MA [1 ]
Ventola, F [1 ]
机构
[1] Univ Roma La Sapienza, Dipartimento Biol Anim & Uomo, I-00185 Rome, Italy
关键词
amphibia; toad; insulin; somatostatin; glucagon; pancreatic polypeptide;
D O I
10.1046/j.1469-7580.1998.19220195.x
中图分类号
R602 [外科病理学、解剖学]; R32 [人体形态学];
学科分类号
100101 ;
摘要
The endocrine pancreas of the toad consists of rounded islets of various sizes embedded in the exocrine tissue. Isolated cells are also present. At least 4 types of endocrine cell are distinguishable by shape, size and electrondensity of the secretory granules as well as by their immunoreactivity with different antisera: insulin, somatostatin, pancreatic polypeptide, and glucagon cells. Insulin cells can be divided into 2 types according to their cytoplasmic electrondensity. Colocalisation of different hormones in the same cell is rarely observed. The close contact between endocrine and exocrine cells and the scarcity of nerve supply is indicative of a paracrine control of hormone secretion.
引用
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页码:195 / 202
页数:8
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