Cell-mediated immunity in allergic bronchopulmonary aspergillosis

被引：28

作者：

Knutsen, AP ^{[1
]}

Chauhan, B ^{[1
]}

Slavin, RG ^{[1
]}

机构：

[1] St Louis Univ, Hlth Sci Ctr, Pediat Res Inst, Div Allergy Immunol, St Louis, MO 63110 USA

来源：

IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA | 1998年 / 18卷 / 03期

关键词：

D O I：

10.1016/S0889-8561(05)70023-0

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

The pathogenesis of ABPA is characterized by a heightened Th2 CD4+ autocrine late-phase allergic inflammatory response to A. fumigatus allergens in the bronchial airway of patients with atopic asthma and patients with CF. in addition, T-cell responses to A. fumigatus allergens are HLA-DR2 and DR5 and TCR-V restricted in ABPA. The underlying susceptibility to develop ABPA versus an asthmatic allergic response to A. fumigatus allergens, however, is not understood.

引用

页码：575 / +

页数：26

共 140 条

[1]

ABUGHAZALEH RI, 1989, J IMMUNOL, V142, P2393

[2]

ACKERMAN SJ, 1983, J IMMUNOL, V131, P2977

[3] Chemokines in allergic inflammation [J].

Alam, R .

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 1997, 99 (03) :273-277

[4]

ARMANT M, 1995, J IMMUNOL, V155, P4868

[5] EXPRESSION AND FUNCTIONAL-ROLE OF CD23 ON T-CELLS [J].

ARMITAGE, RJ ;

GOFF, LK ;

BEVERLEY, PCL .

EUROPEAN JOURNAL OF IMMUNOLOGY, 1989, 19 (01) :31-35

[6] ASPERGILLUS-FUMIGATUS ALLERGEN-I, A MAJOR IGE-BINDING PROTEIN, IS A MEMBER OF THE MITOGILLIN FAMILY OF CYTOTOXINS [J].

ARRUDA, LK ;

PLATTSMILLS, TAE ;

FOX, JW ;

CHAPMAN, MD .

JOURNAL OF EXPERIMENTAL MEDICINE, 1990, 172 (05) :1529-1532

[7] ASPERGILLUS-FUMIGATUS - IDENTIFICATION OF 16, 18, AND 45 KD ANTIGENS RECOGNIZED BY HUMAN-IGG AND IGE ANTIBODIES AND MURINE MONOCLONAL-ANTIBODIES [J].

ARRUDA, LK ;

PLATTSMILLS, TAE ;

LONGBOTTOM, JL ;

ELDAHR, JM ;

CHAPMAN, MD .

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 1992, 89 (06) :1166-1176

[8]

ARRUDA LK, 1995, INT ARCH ALLERGY IMM, V107, P410, DOI 10.1159/000237057

[9] New frontiers for IL-5 [J].

Bagley, CJ ;

Lopez, AF ;

Vadas, MA .

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 1997, 99 (06) :725-728

[10] Prevalence of allergic bronchopulmonary aspergillosis and atopy in adult patients with cystic fibrosis [J].

Becker, JW ;

Burke, W ;

McDonald, G ;

Greenberger, PA ;

Henderson, WR ;

Aitken, ML .

CHEST, 1996, 109 (06) :1536-1540

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