High-affinity multivalent DNA binding by using low-molecular-weight dendrons

被引：108

作者：

Kostiainen, MA ^{[1
]}

Hardy, JG ^{[1
]}

Smith, DK ^{[1
]}

机构：

[1] Univ York, Dept Chem, York YO10 5DD, N Yorkshire, England

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2005年 / 44卷 / 17期

关键词：

dendrimers; DNA; multivalency; nanochemistry; self-assembly;

D O I：

10.1002/anie.200500066

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Chemical Equation Presented) Nine spermines are better than one: Compound C2 exhibits high-affinity, salt-independent DNA binding as a consequence of the spermine array on its surface. Comparison with smaller dendrons and model compounds indicates a clear multivalency effect on binding. © 2005 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：2556 / 2559

页数：4

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