Dexmedetomidine as sole sedative for awake intubation in management of the critical airway

被引：111

作者：

Abdelmalak, Basem

Makary, Laila

Hoban, Jeremy

Doyle, D. John

机构：

[1] Cleveland Clin, Dept Gen Anesthesiol, Cleveland, OH 44195 USA

[2] Cleveland Clin, Dept Outcomes Res, Cleveland, OH 44195 USA

[3] Cleveland Clin, Div Anesthesiol Crit Care Med & Comprehens Pain M, Cleveland, OH 44195 USA

[4] Case Western Reserve Univ, Coll Med, Cleveland Clin Lerner, Cleveland, OH 44195 USA

来源：

JOURNAL OF CLINICAL ANESTHESIA | 2007年 / 19卷 / 05期

关键词：

dexmedetomidine; difficult airway; awake intubation; fiberoptic bronchoscopy; sedation;

D O I：

10.1016/j.jclinane.2006.09.006

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

We report a series of successful awake fiberoptic intubations in patients with critical (unstable, difficult) airways using the (alpha(2)-agonist, dexmedetomidine. Dexmedetomidine has several desirable pharmacologic properties, including sedation, anxiolysis, hypnosis, analgesia, amnesia, antisialagogue effects, and a unique respiratory-sparing effect. Dexmedetomidine appears to be a useful agent for sedation during awake fiberoptic intubation in difficult airway patients. (c) 2007 Elsevier Inc. All rights reserved.

引用

页码：370 / 373

页数：4

共 8 条

[1] EFFECTS OF INTRAVENOUS DEXMEDETOMIDINE IN HUMANS .1. SEDATION, VENTILATION, AND METABOLIC-RATE [J].