Membrane-associated CD40L and sCD40L in atherothrombotic disease

被引：132

作者：

Anand, SX

Viles-Gonzalez, JF

Badimon, JJ

Cavusoglu, E

Marmur, JD

机构：

[1] SUNY Hlth Sci Ctr, Dept Med, Div Cardiol, Brooklyn, NY 11203 USA

[2] CUNY Mt Sinai Sch Med, Zena & Michael A Weiner Cardiovasc Inst, New York, NY 10029 USA

来源：

THROMBOSIS AND HAEMOSTASIS | 2003年 / 90卷 / 03期

关键词：

CD40L; atherothrombotic disease; platelets; extracellular matrix; matrix metalloproteinase;

D O I：

10.1160/TH03-05-0268

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Recent data suggests that CD40L is involved in the pathogenesis of atherothrombotic disease. This review will focus on the history of CD40L, its role in platelet-mediated pathogenesis of atherothrombotic disease, its association to clinical syndromes and procedures, and its role in determining plaque rupture.

引用

收藏

页码：377 / 384

页数：8

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