Prevention and therapy in hereditary retinal degenerations

被引：11

作者：

Besch, D ^{[1
]}

Zrenner, E ^{[1
]}

机构：

[1] Univ Eye Hosp, Dept Patholphysiolm Vis & Neuroophthalmol, D-72076 Tubingen, Germany

来源：

DOCUMENTA OPHTHALMOLOGICA | 2003年 / 106卷 / 01期

关键词：

counselling; prevention; retinal degeneration; therapy;

D O I：

10.1023/A:1022427813898

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

A survey of the present state of developments concerning prevention and therapy of hereditary retinal diseases is given. In recent years the techniques of molecular genetics have led to a rapid identification of a great number of cloned or mapped genes responsible for such diseases. Moreover, further progress has been made in the understanding of disease mechanisms by describing the defective proteins and their altered metabolism. The most recent preventive and therapeutic strategies including gene therapy, dietary regimens, anti-apoptotic agents, transplantation and retinal prosthesis are discussed.

引用

页码：31 / 35

页数：5

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