A comparison of laser photocoagulation with trans-scleral cryotherapy in the treatment of threshold retinopathy of prematurity

被引:60
作者
Connolly, BP [1 ]
McNamara, JA [1 ]
Sharma, S [1 ]
Regillo, CD [1 ]
Tasman, W [1 ]
机构
[1] Thomas Jefferson Univ, Jefferson Med Coll, Wills Eye Hosp, Off OIC, Philadelphia, PA 19107 USA
关键词
D O I
10.1016/S0161-6420(98)99029-7
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Objective: The goal of this study was to determine whether there was a significant difference between the visual outcomes of eyes with threshold retinopathy of prematurity (ROP) treated with trans-scleral cryotherapy compared to those treated with laser photocoagulation. Design: Extended follow-up study of a prospective, randomized clinical trial. Participants: Fifty-two patients with bilateral threshold ROP participated. Follow-up data were available for 25 of these patients. Intervention: Patients were randomized to receive cryotherapy in one eye and laser photocoagulation in the other eye. Main Outcome Measures: The best-corrected visual acuity of each eye was measured. Best-corrected visual acuities of 20/50 or better were classified as "good" clinical outcomes, whereas those 20/60 or worse were considered "poor" outcomes. A secondary outcome of this study was the spherical equivalent (SE) of each eye's most recent refraction. Result: At an average follow-up point of 5.8 years (range, 4.3-7.6 years), the odds that an eye treated with laser had a good clinical outcome were 6.91 times greater than for eyes treated with cryotherapy (95% confidence interval, 1.70-28.0; n = 21). Additionally, the laser-treated eyes were less myopic with a mean SE of -3.05 diopters compared to a mean SE of -5.08 diopters for the cryotherapy-treated eyes (P = 0.0072, n = 23). Conclusion: The authors' study suggests that laser photocoagulation for threshold ROP was more likely to result in a good clinical outcome with better final visual acuity and less myopia compared to cryotherapy treatment.
引用
收藏
页码:1628 / 1631
页数:4
相关论文
共 15 条
[1]   REFRACTIVE OUTCOME FOLLOWING DIODE-LASER VERSUS CRYOTHERAPY FOR EYES WITH RETINOPATHY OF PREMATURITY [J].
ALGAWI, K ;
GOGGIN, M ;
OKEEFE, M .
BRITISH JOURNAL OF OPHTHALMOLOGY, 1994, 78 (08) :612-614
[2]  
*AM AC PED AM ASS, 1997, OPHTHALMOLOGY, V104, P888
[3]  
BRANCATO R, 1989, INVEST OPHTH VIS SCI, V30, P1504
[4]   DIODE-LASER PHOTOCOAGULATION FOR ZONE-1 THRESHOLD RETINOPATHY OF PREMATURITY [J].
CAPONE, A ;
DIAZROHENA, R ;
STERNBERG, P ;
MANDELL, B ;
LAMBERT, M ;
LOPEZ, PF .
AMERICAN JOURNAL OF OPHTHALMOLOGY, 1993, 116 (04) :444-450
[5]  
Elsas FJ, 1996, ARCH OPHTHALMOL-CHIC, V114, P417
[6]   LASER PHOTOCOAGULATION FOR THRESHOLD RETINOPATHY OF PREMATURITY [J].
IVERSON, DA ;
TRESE, MT ;
ORGEL, IK ;
WILLIAMS, GA .
ARCHIVES OF OPHTHALMOLOGY, 1991, 109 (10) :1342-1343
[7]  
KNAPP RG, 1992, CLIN EPIDEMIOLOGY BI, P233
[8]   Refractive outcome in eyes with retinopathy of prematurity treated with cryotherapy or diode laser: 3 year follow up [J].
KnightNanan, DM ;
OKeefe, M .
BRITISH JOURNAL OF OPHTHALMOLOGY, 1996, 80 (11) :998-1001
[9]   TREATMENT OF RETINOPATHY OF PREMATURITY WITH ARGON-LASER PHOTOCOAGULATION [J].
LANDERS, MB ;
TOTH, CA ;
SEMPLE, HC ;
MORSE, LS .
ARCHIVES OF OPHTHALMOLOGY, 1992, 110 (01) :44-47
[10]  
MCNAMARA JA, 1991, OPHTHALMOLOGY, V98, P576