The Tol-Pal proteins of the Escherichia coli cell envelope:: an energized system required for outer membrane integrity?

被引：147

作者：

Lloubès, R ^{[1
]}

Cascales, E ^{[1
]}

Walburger, A ^{[1
]}

Bouveret, E ^{[1
]}

Lazdunski, C ^{[1
]}

Bernadac, A ^{[1
]}

Journet, L ^{[1
]}

机构：

[1] Inst Biol Struct & Microbiol, CNRS, UPR 9027, F-13402 Marseille 20, France

来源：

RESEARCH IN MICROBIOLOGY | 2001年 / 152卷 / 06期

关键词：

Tol-Pal and TonB systems; outer membrane integrity; proton motive force;

D O I：

10.1016/S0923-2508(01)01226-8

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The outer membrane of Gram-negative bacteria acts as a barrier against harmful lipophilic compounds and larger molecules unable to diffuse freely through the porins. However, outer membrane proteins together with the Tol-Pal and TonB systems have been exploited for the entry of macromolecules such as bacteriocins and phage DNA through the Escherichia coli cell envelope. The TonB system is involved in the active transport of iron siderophores and vitamin B12, while no more precise physiological role of the Tol-Pal system has yet been defined than its requirement for cell envelope integrity. These two systems, containing an energized inner membrane protein interacting with outer membrane proteins, share similarities. (C) 2001 Editions scientifiques et medicales Elsevier SAS.

引用

页码：523 / 529

页数：7

共 48 条

[1] Structure of the Escherichia coli TolB protein determined by MAD methods at 1.95 Å resolution [J].

Abergel, C ;

Bouveret, E ;

Claverie, JM ;

Brown, K ;

Rigal, A ;

Lazdunski, C ;

Bénédetti, H .

STRUCTURE, 1999, 7 (10) :1291-1300

[2] Crystallization and preliminary crystallographic study of the peptidoglycan-associated lipoprotein from Escherichia coli [J].

Abergel, C ;

Walburger, A ;

Chenivesse, S ;

Lazdunski, C .

ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY, 2001, 57 :317-319

[3] Crystallization and preliminary crystallographic study of the periplasmic domain of the Escherichia coli TolR protein [J].

Abergel, C ;

Journet, L ;

Chenivesse, S ;

Gavioli, M ;

Lloubès, R .

ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY, 2001, 57 :323-325

[4] Chunnel vision - Export and efflux through bacterial channel-tunnels [J].

Andersen, C ;

Hughes, C ;

Koronakis, V .

EMBO REPORTS, 2000, 1 (04) :313-318

[5] Escherichia coli tol-pal mutants form outer membrane vesicles [J].

Bernadac, A ;

Gavioli, M ;

Lazzaroni, JC ;

Raina, S ;

Lloubès, R .

JOURNAL OF BACTERIOLOGY, 1998, 180 (18) :4872-4878

[6] Distinct regions of the colicin A translocation domain are involved in the interaction with TolA and TolB proteins upon import into Escherichia coli [J].

Bouveret, E ;

Rigal, A ;

Lazdunski, C ;

Bénédetti, H .

MOLECULAR MICROBIOLOGY, 1998, 27 (01) :143-157

[7] PEPTIDOGLYCAN-ASSOCIATED LIPOPROTEIN-TOLB INTERACTION [J].

BOUVERET, E ;

DEROUICHE, R ;

RIGAL, A ;

LLOUBES, R ;

LAZDUNSKI, C ;

BENEDETTI, H .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1995, 270 (19) :11071-11077

[8] At least four percent of the Salmonella typhimurium genome is required for fatal infection of mice [J].

Bowe, F ;

Lipps, CJ ;

Tsolis, RM ;

Groisman, E ;

Heffron, F ;

Kusters, JG .

INFECTION AND IMMUNITY, 1998, 66 (07) :3372-3377

[9]

BRAUN V, 1995, FEMS MICROBIOL REV, V16, P295, DOI 10.1016/0168-6445(95)00003-U

[10] EVOLUTIONARY RELATIONSHIP OF UPTAKE SYSTEMS FOR BIOPOLYMERS IN ESCHERICHIA-COLI - CROSS-COMPLEMENTATION BETWEEN THE TONB EXBB EXBD AND THE TOLA TOLQ TOLR PROTEINS [J].

BRAUN, V ;

HERRMANN, C .

MOLECULAR MICROBIOLOGY, 1993, 8 (02) :261-268

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