Interferon-β treatment in patients with childhood onset multiple sclerosis

被引：88

作者：

Mikaelloff, Y

Moreau, T

Debouverie, M

Pelletier, J

Lebrun, C

Gout, O

Pedespan, JM

Van Hulle, C

Vermersch, P

Ponsot, G

机构：

[1] Hop St Vincent de Paul, Serv Neurol Pediat, Dept Neuropediat, F-75674 Paris 14, France

[2] Univ Hosp, Bordeaux, France

[3] Univ Rouen, Hosp, Rouen, France

[4] Univ Dijon, Hosp, Dept Neurol, F-21004 Dijon, France

[5] Nancy Univ Hosp, Nancy, France

[6] Univ Hosp, Marseille, France

[7] Univ Nice, Hosp, Nice, France

[8] Hop La Pitie Salpetriere, Paris, France

[9] Univ Lille, Hosp, Lille, France

来源：

JOURNAL OF PEDIATRICS | 2001年 / 139卷 / 03期

关键词：

D O I：

10.1067/mpd.2001.117004

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

We present a report of the use of interferon-beta before 18 years of age in 16 patients with childhood-onset multiple sclerosis. This study demonstrated that the treatment is safe and well tolerated.

引用

页码：443 / 446

页数：4

共 11 条

[1] INTERFERON BETA-1B IS EFFECTIVE IN RELAPSING-REMITTING MULTIPLE-SCLEROSIS - CLINICAL-RESULTS OF A MULTICENTER, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL [J].

DUQUETTE, P ;

GIRARD, M ;

DESPAULT, L ;

DUBOIS, R ;

KNOBLER, RL ;

LUBLIN, FD ;

KELLEY, L ;

FRANCIS, GS ;

LAPIERRE, Y ;

ANTEL, J ;

FREEDMAN, M ;

HUM, S ;

GREENSTEIN, JI ;

MISHRA, B ;

MULDOON, J ;

WHITAKER, JN ;

EVANS, BK ;

LAYTON, B ;

SIBLEY, WA ;

LAGUNA, J ;

KRIKAWA, J ;

PATY, DW ;

OGER, JJ ;

KASTRUKOFF, LF ;

MOORE, GRW ;

HASHIMOTO, SA ;

MORRISON, W ;

NELSON, J ;

GOODIN, DS ;

MASSA, SM ;

GUTTERIDGE, E ;

ARNASON, BGW ;

NORONHA, A ;

REDER, AT ;

MARTIA, R ;

EBERS, GC ;

RICE, GPA ;

LESAUX, J ;

JOHNSON, KP ;

PANITCH, HS ;

BEVER, CT ;

CONWAY, K ;

WALLENBERG, JC ;

BEDELL, L ;

VANDENNOORT, S ;

WEINSHENKER, B ;

WEISS, W ;

REINGOLD, S ;

PACHNER, A ;

TAYLOR, W .

NEUROLOGY, 1993, 43 (04) :655-661

[2] MULTIPLE-SCLEROSIS IN CHILDHOOD - CLINICAL PROFILE IN 125 PATIENTS [J].

DUQUETTE, P ;

MURRAY, TJ ;

PLEINES, J ;

EBERS, GC ;

SADOVNICK, D ;

WELDON, P ;

WARREN, S ;

PATY, DW ;

UPTON, A ;

HADER, W ;

NELSON, R ;

AUTY, A ;

NEUFELD, B ;

MELTZER, C .

JOURNAL OF PEDIATRICS, 1987, 111 (03) :359-363

[3] Randomised double-blind placebo-controlled study of interferon β-1a in relapsing/remitting multiple sclerosis [J].

Ebers, GC ;

Rice, G ;

Lesaux, J ;

Paty, D ;

Oger, J ;

Li, DKB ;

Beall, S ;

Devonshire, V ;

Hashimoto, S ;

Hooge, J ;

Kastrukoff, L ;

Krieger, C ;

Mezei, M ;

Seland, P ;

Vorobeychi, G ;

Morrison, W ;

Nelson, J ;

Freedman, MS ;

Chrisie, S ;

Nelson, R ;

Rabinovitch, H ;

Freedman, C ;

Hartung, HP ;

Rieckmann, P ;

Archelos, J ;

Jung, S ;

Weilbach, F ;

Flachenecke, P ;

Sauer, J ;

Hommes, O ;

Jongen, P ;

Brouwer, S ;

McLeod, J ;

Pollard, J ;

Ng, R ;

Sandberg-Wollheim, M ;

Källén, K ;

Nilsson, P ;

Ekberg, R ;

Lundgren, A ;

Jadbäck, G ;

Wikström, J ;

Multanen, J ;

Valjakka, M ;

Carton, H ;

Lissoir, F ;

Declerq, I ;

Vieren, M ;

Peeters, E ;

Dubois, B .

LANCET, 1998, 352 (9139) :1498-1504

[4] Multiple sclerosis in childhood: Clinical features of 149 cases [J].

Ghezzi, A ;

Deplano, V ;

Faroni, J ;

Grasso, MG ;

Liguori, M ;

Marrosu, G ;

Pozzilli, C ;

Simone, IL ;

Zaffaroni, M .

MULTIPLE SCLEROSIS, 1997, 3 (01) :43-46

[5] Interferon β therapy for multiple sclerosis [J].

Goodkin, DE .

LANCET, 1998, 352 (9139) :1486-1487

[6]

HANEFELD FA, 1994, INT MSJ, V1, P91

[7] Intramuscular interferon beta-1a therapy initiated during a first demyelinating event in multiple sclerosis. [J].

Jacobs, LD ;

Beck, RW ;

Simon, JH ;

Kinkel, RP ;

Brownscheidle, CM ;

Murray, TJ ;

Simonian, NA ;

Slasor, PJ ;

Sandrock, AW .

NEW ENGLAND JOURNAL OF MEDICINE, 2000, 343 (13) :898-904

[8] Intramuscular interferon beta-1 alpha for disease progression in relapsing multiple sclerosis [J].

Jacobs, LD ;

Cookfair, DL ;

Rudick, RA ;

Herndon, RM ;

Richert, JR ;

Salazar, AM ;

Fischer, JS ;

Goodkin, DE ;

Granger, CV ;

Simon, JH ;

Alam, JJ ;

Bartoszak, DM ;

Bourdette, DN ;

Braiman, J ;

Brownscheidle, CM ;

Coats, ME ;

Cohan, SL ;

Dougherty, DS ;

Kinkel, RP ;

Mass, MK ;

Munschauer, FE ;

Priore, RL ;

Pullicino, PM ;

Scherokman, BJ ;

WeinstockGuttman, B ;

Whitman, RH ;

Baird, WC ;

Fillmore, M ;

Bona, LM ;

ColonRuiz, ME ;

Nadine, BS ;

Donovan, A ;

Bennett, S ;

Kieffer, YM ;

Umhauer, MA ;

Miller, CE ;

Kilic, AK ;

Sargent, EL ;

Schachter, M ;

Shucard, DW ;

Weider, V ;

Catalano, BA ;

Cervi, JM ;

Czekay, C ;

Farrell, JL ;

Filippini, JS ;

Matyas, RC ;

Michienzi, KE ;

Ito, M ;

OMalley, JA .

ANNALS OF NEUROLOGY, 1996, 39 (03) :285-294

[9]

KURTZKE JF, 1983, NEUROLOGY, V33, P1444, DOI 10.1212/WNL.33.11.1444

[10] NEW DIAGNOSTIC-CRITERIA FOR MULTIPLE-SCLEROSIS - GUIDELINES FOR RESEARCH PROTOCOLS [J].

POSER, CM ;

PATY, DW ;

SCHEINBERG, L ;

MCDONALD, WI ;

DAVIS, FA ;

EBERS, GC ;

JOHNSON, KP ;

SIBLEY, WA ;

SILBERBERG, DH ;

TOURTELLOTTE, WW .

ANNALS OF NEUROLOGY, 1983, 13 (03) :227-231

← 1 2 →