Antibody engineering

被引：74

作者：

Dall'Acqua, W ^{[1
]}

Carter, P ^{[1
]}

机构：

[1] Genentech Inc, Dept Mol Oncol, S San Francisco, CA 94080 USA

来源：

CURRENT OPINION IN STRUCTURAL BIOLOGY | 1998年 / 8卷 / 04期

关键词：

D O I：

10.1016/S0959-440X(98)80121-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Among the most important advances in antibody engineering of this past year is the advent of new tools to study the relationship between protein (including antibody) structure and function. Very rapid large-scale mutational analysis of antibodies is now possible by using in vitro transcription and translation. Ribosome display is a rapidly evolving technology for modifying antibody function that offers several potential advantages over phage display.

引用

页码：443 / 450

页数：8

共 70 条

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