Autoimmune hepatitis following infliximab therapy for ankylosing spondylitis

被引:55
作者
Ozorio, Gerard [1 ]
McGarity, Bruce [2 ]
Bak, Haesung [3 ]
Jordan, Andrew S. [3 ]
Lau, Henry [4 ]
Marshall, Cathy
机构
[1] Royal Prince Alfred Hosp, Sydney, NSW, Australia
[2] Bathurst Base Hosp, Bathurst, NSW, Australia
[3] Westmead Hosp, Sydney, NSW, Australia
[4] Orange Base Hosp, Orange, NSW, Australia
关键词
D O I
10.5694/j.1326-5377.2007.tb01396.x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Autoimmune hepatitis is a rare but increasingly recognised serious complication of treatment with the tumour necrosis factor-alpha (TNF-alpha) blocking agent, infliximab. This report adds to the small but growing number of articles describing this significant adverse effect. Baseline liver function should be routinely tested in all patients receiving anti-TNF-alpha agents, and periodic monitoring for the development of hepatitis is important.
引用
收藏
页码:524 / 526
页数:3
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