Life with nucleosomes:: chromatin remodelling in gene regulation

被引:46
作者
Gregory, PD [1 ]
Hörz, W [1 ]
机构
[1] Univ Munich, Inst Physiol Chem, D-80336 Munich, Germany
关键词
D O I
10.1016/S0955-0674(98)80009-4
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
In the past year, the role of chromatin has emerged at the forefront of transcription research. Discovery and characterisation of the chromatin modifying machinery have significantly advanced our understanding of the molecular activities that establish a transcriptionally competent substrate in vivo, and have underscored the importance of the part played by chromatin in the regulation of transcription.
引用
收藏
页码:339 / 345
页数:7
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共 73 条
  • [1] Role for N-CoR and histone deacetylase in Sin3-mediated transcriptional repression
    Alland, L
    Muhle, R
    Hou, H
    Potes, J
    Chin, L
    SchreiberAgus, N
    DePinho, RA
    [J]. NATURE, 1997, 387 (6628) : 49 - 55
  • [2] The CBP co-activator is a histone acetyltransferase
    Bannister, AJ
    Kouzarides, T
    [J]. NATURE, 1996, 384 (6610) : 641 - 643
  • [3] CHARACTERIZATION OF PHYSICAL INTERACTIONS OF THE PUTATIVE TRANSCRIPTIONAL ADAPTER, ADA2, WITH ACIDIC ACTIVATION DOMAINS AND TATA-BINDING PROTEIN
    BARLEV, NA
    CANDAU, R
    WANG, LA
    DARPINO, P
    SILVERMAN, N
    BERGER, SL
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1995, 270 (33) : 19337 - 19344
  • [4] Chromatin structure and the regulation of gene expression: Remodeling at the MMTV promoter
    Beato, M
    [J]. JOURNAL OF MOLECULAR MEDICINE-JMM, 1996, 74 (12): : 711 - 724
  • [5] Retinoid-induced chromatin structure alterations in the retinoic acid receptor beta 2 promoter
    Bhattacharyya, N
    Dey, A
    Minucci, S
    Zimmer, A
    John, S
    Hager, G
    Ozato, K
    [J]. MOLECULAR AND CELLULAR BIOLOGY, 1997, 17 (11) : 6481 - 6490
  • [6] Retinoblastoma protein recruits histone deacetylase to repress transcription
    Brehm, A
    Miska, EA
    McCance, DJ
    Reid, JL
    Bannister, AJ
    Kouzarides, T
    [J]. NATURE, 1998, 391 (6667) : 597 - 601
  • [7] Disruption of downstream chromatin directed by a transcriptional activator
    Brown, SA
    Kingston, RE
    [J]. GENES & DEVELOPMENT, 1997, 11 (23) : 3116 - 3121
  • [8] Tetrahymena histone acetyltransferase A: A homolog to yeast Gcn5p linking histone acetylation to gene activation
    Brownell, JE
    Zhou, JX
    Ranalli, T
    Kobayashi, R
    Edmondson, DG
    Roth, SY
    Allis, CD
    [J]. CELL, 1996, 84 (06) : 843 - 851
  • [9] The yeast SWI-SNF complex facilitates binding of a transcriptional activator to nucleosomal sites in vivo
    Burns, LG
    Peterson, CL
    [J]. MOLECULAR AND CELLULAR BIOLOGY, 1997, 17 (08) : 4811 - 4819
  • [10] RSC, an essential, abundant chromatin-remodeling complex
    Cairns, BR
    Lorch, Y
    Li, Y
    Zhang, MC
    Lacomis, L
    ErdjumentBromage, H
    Tempst, P
    Du, J
    Laurent, B
    Kornberg, RD
    [J]. CELL, 1996, 87 (07) : 1249 - 1260