Mycobacterium tuberculosis in the post-genomic age

被引:36
作者
Domenech, P
Barry, CE
Cole, ST
机构
[1] Inst Pasteur, Unite Genet Mol Bacterienne, F-75724 Paris 15, France
[2] NIAID, TB Res Sect, Host Def Lab, NIH, Rockville, MD 20852 USA
关键词
D O I
10.1016/S1369-5274(00)00160-0
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Since the publication of the complete genome sequence of Mycobacterium tuberculosis in 1998, there has been a marked intensification and diversification of activities in the field of tuberculosis research. Among the areas that have advanced spectacularly are comparative genomics, functional genomics - notably the study of the transcriptome and proteome - and cell envelope biogenesis, especially as it relates to the mechanism of action of antimycobacterial drugs.
引用
收藏
页码:28 / 34
页数:7
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