Novel Structural Elements within the Nonproteolytic Clostridium botulinum Type F Toxin Gene Cluster

被引：12

作者：

Dover, N. ^{[1
]}

Barash, J. R. ^{[1
]}

Hill, K. K. ^{[2
]}

Detter, J. C. ^{[2
]}

Arnon, S. S. ^{[1
]}

机构：

[1] Calif Dept Publ Hlth, Infant Botulism Treatment & Prevent Program, Richmond, CA 94804 USA

[2] Los Alamos Natl Lab, Biosci Div, Los Alamos, NM USA

来源：

APPLIED AND ENVIRONMENTAL MICROBIOLOGY | 2011年 / 77卷 / 05期

关键词：

PROTEIN GENES; NEUROTOXIN; STRAINS; ARRANGEMENT; EXPRESSION; DIVERSITY; BOTR/A;

D O I：

10.1128/AEM.02422-10

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

We sequenced for the first time the complete neurotoxin gene cluster of a nonproteolytic Clostridium botulinum type F. The neurotoxin gene cluster contained a novel gene arrangement that, compared to other C. botulinum neurotoxin gene clusters, lacked the regulatory botR gene and contained an intergenic is element between its orfX2 and orfX3 genes.

引用

页码：1904 / 1906

页数：3

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