An outbreak of carbapenem-resistant Acinetobacter baumannii producing OXA-23 carbapenemase in western China

被引：53

作者：

Zong, Zhiyong ^{[1
,2
]}

Lue, Xiaoju ^{[2
]}

Valenzuela, Jubelle K. ^{[1
]}

Partridge, Sally R. ^{[1
]}

Iredell, Jon ^{[1
]}

机构：

[1] Univ Sydney, Westmead Hosp, Ctr Infect Dis & Microbiol, Westmead, NSW 2145, Australia

[2] Sichuan Univ, W China Hosp, Dept Infect Dis, Chengdu 610064, Peoples R China

来源：

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS | 2008年 / 31卷 / 01期

基金：

英国医学研究理事会;

关键词：

oxacillinase; carbapenemase; Acinetobacter baumannii; integron; Acinetobacter-derived cephalosporinase;

D O I：

10.1016/j.ijantimicag.2007.08.019

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Twenty-two non-repetitive carbapenem-resistant Acinetobacter baumannii isolates were obtained from Intensive Care Unit patients. All of the isolates carried bla(OXA-23), bla(OXA-66), a novel cephalosporinase-encoding gene (bla(ADC-25)) and a class 1 integron with an aacCI-orfP-orfQ-aadAIa cassette array and had identical enterobacterial repetitive intergenic consensus (ERIC) profiles. ISAba1 was found upstream of bla(OXA-23), but was not associated with bla(OXA-66) or b/a(ADC-25). (C) 2007 Elsevier B.V. and the International Society of Chemotherapy. All rights reserved.

引用

页码：50 / 54

页数：5

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