CrossChip: a system supporting comparative analysis of different generations of Affymetrix arrays

被引：12

作者：

Kong, SW ^{[1
]}

Hwang, KB

Zhang, BT

Greenberg, SA

Kohane, IS

Park, PJ

机构：

[1] Harvard Univ, Bauer Ctr Genom Res, Cambridge, MA 02138 USA

[2] Beth Israel Deaconess Med Ctr, Boston, MA 02215 USA

[3] Seoul Natl Univ, Sch Engn & Comp Sci, Seoul 151, South Korea

[4] Harvard Partners Ctr Genet & Genom, Boston, MA USA

[5] Brigham & Womens Hosp, Dept Neurol, Boston, MA 02115 USA

[6] Childrens Hosp, Informat Program, Boston, MA 02115 USA

来源：

BIOINFORMATICS | 2005年 / 21卷 / 09期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1093/bioinformatics/bti288

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

To increase compatibility between different generations of Affymetrix GeneChip arrays, we propose a method of filtering probes based on their sequences. Our method is implemented as a web-based service for downloading necessary materials for converting the raw data files (*.CEL) for comparative analysis. The user can specify the appropriate level of filtering by setting the criteria for the minimum overlap length between probe sequences and the minimum number of usable probe pairs per probe set. Our website supports a within-species comparison for human and mouse GeneChip arrays.

引用

页码：2116 / 2117

页数：2

共 4 条

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