The concentration of apolipoprotein A-I decreases during experimentally induced acute-phase processes in pigs

被引:53
作者
Carpintero, R
Piñeiro, M
Andrés, M
Iturralde, M
Alava, MA
Heegaard, PMH
Jobert, JL
Madec, F
Lampreave, F [1 ]
机构
[1] Univ Zaragoza, Fac Ciencias, Dept Bioquim & Biol Mol & Celular, E-50009 Zaragoza, Spain
[2] Danish Inst Food & Vet Res, Copenhagen V, Denmark
[3] French Agcy Food Safety, F-22440 Ploufragan, France
关键词
D O I
10.1128/IAI.73.5.3184-3187.2005
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
In this work, apolipoprotein A-I (ApoA-I) was purified from pig sera. The responses of this protein after sterile inflammation and in animals infected with Actinobacillus pleuropneumoniae or Streptococcus suis were investigated. Decreases in the concentrations of ApoA-I, two to five times lower than the initial values, were observed at 2 to 4 days. It is concluded that ApoA-I is a negative acute-phase protein in pigs.
引用
收藏
页码:3184 / 3187
页数:4
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