RETRACTED: Mediation of pathogen resistance by exudation of antimicrobials from roots (Retracted Article)

被引:111
作者
Bais, HP
Prithiviraj, B
Jha, AK
Ausubel, FM [1 ]
Vivanco, JM
机构
[1] Colorado State Univ, Dept Hort & Landscape Architecture, Ft Collins, CO 80523 USA
[2] Colorado State Univ, Ctr Rhizosphere Biol, Ft Collins, CO 80523 USA
[3] Harvard Univ, Sch Med, Dept Genet, Boston, MA 02114 USA
[4] Massachusetts Gen Hosp, Dept Mol Biol, Boston, MA 02114 USA
基金
美国国家科学基金会; 美国国家卫生研究院; 英国惠康基金;
关键词
D O I
10.1038/nature03356
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Most plant species are resistant to most potential pathogens. It is not known why most plant - microbe interactions do not lead to disease, although recent work indicates that this basic disease resistance is multi-factorial(1,2). Here we show that the exudation of root-derived antimicrobial metabolites by Arabidopsis thaliana confers tissue-specific resistance to a wide range of bacterial pathogens. However, a Pseudomonas syringae strain that is both at least partly resistant to these compounds and capable of blocking their synthesis/exudation is able to infect the roots and cause disease. We also show that the ability of this P. syringae strain to block antimicrobial exudation is dependent on the type III secretory system.
引用
收藏
页码:217 / 221
页数:5
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