Antiviral evaluation of plants from Brazilian Atlantic Tropical Forest

被引：55

作者：

Andrighetti-Fröhner, CR

Sincero, TCM

da Silva, AC

Savi, LA

Gaido, CM

Bettega, JMR

Mancini, M

de Almeida, MTR

Barbosa, RA

Farias, MR

Barardi, CRM

Simoes, CMO

机构：

[1] Univ Fed Santa Catarina, Lab Virol Aplicada, Florianopolis, SC, Brazil

[2] Univ Fed Santa Catarina, Lab Farmacognosia, Florianopolis, SC, Brazil

[3] Univ Fed Santa Catarina, Dept Ciencias Farmaceut, Florianopolis, SC, Brazil

[4] Univ Fed Santa Catarina, Dept Microbiol & Parasitol, Florianopolis, SC, Brazil

来源：

FITOTERAPIA | 2005年 / 76卷 / 3-4期

关键词：

antiviral; Herpes simplex virus type 1; poliovirus type 2; Brazilian medicinal plants;

D O I：

10.1016/j.fitote.2005.03.010

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The antiviral activity of six medicinal plants from Brazilian Atlantic Tropical Forest was investigated against two viruses: Herpes simplex virus type 1 (HSV-1) and poliovirus type 2 (PV-2). Cuphea carthagenensis and Tillandsia usneoides extracts showed the best antiherpes activity. T usneoides dichloromethane, ethyl acetate and n-butanol extracts, and Lippia alba n-butanol extract showed inhibition of HSV-1, strain 29R/acyclovir resistant. In addition, only L. alba ethyl acetate extract showed antipoliovirus activity. These results corroborate that medicinal plants can be a rich source of potential antiviral compounds. (c) 2005 Elsevier B.V. All rights reserved.

引用

页码：374 / 378

页数：5

共 25 条

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