Clinical options for imipramine in the management of urinary incontinence

被引:37
作者
Hunsballe, JM [1 ]
Djurhuus, JC
机构
[1] Univ Aarhus, Skejby Univ Hosp, Inst Expt Clin Res, Int Enuresis Res Ctr, DK-8200 Aarhus N, Denmark
[2] Aarhus Univ Hosp, Dept Neurol, DK-8000 Aarhus, Denmark
来源
UROLOGICAL RESEARCH | 2001年 / 29卷 / 02期
关键词
imipramine; incontinence; treatment; tricyclic antidepressants; urinary;
D O I
10.1007/s002400100175
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Urinary incontinence is a common disorder in both childhood and adulthood. Proper treatment depends on insight into the pathophysiology and pharmacology of the lower urinary tract. This article reviews the mechanism of action of an old but commonly used drug, the tricyclic antidepressant agent imipramine, in nocturnal enuresis and stress and urge incontinence with reference to neuropharmacology and the relevant pathophysiology.
引用
收藏
页码:118 / 125
页数:8
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