Deletion mapping of the encephalomyocarditis virus primary cleavage site

被引:22
作者
Hahn, H
Palmenberg, AC
机构
[1] Univ Wisconsin, Dept Biochem, Madison, WI 53706 USA
[2] Univ Wisconsin, Inst Mol Virol, Madison, WI 53706 USA
关键词
D O I
10.1128/JVI.75.15.7215-7218.2001
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The cotranslational, primary self-cleavage reaction of cardiovirus polyprotein relies on a highly conserved, short segment of amino acids at the 2A-2B protein boundary. The amino terminus of the required element for encephalomyocarditis virus has now been mapped to include Tyr(126) of the 2A protein, the 18th amino acid before the cleavage site.
引用
收藏
页码:7215 / 7218
页数:4
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