Electrophysiological properties of rat subicular neurons in vitro

被引:34
作者
Behr, J
Empson, RM
Schmitz, D
Gloveli, T
Heinemann, U
机构
[1] Inst. of Physiol. at the Charite, Department of Neurophysiology, Humboldt University Berlin, D-10117 Berlin
关键词
subiculum; intracellular recording; bursting cells; regular firing cells; accommodation; afterhyperpolarization;
D O I
10.1016/S0304-3940(96)13242-0
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
The electrophysiological properties of 46 bursting cells and 39 regular firing cells were studied in the subiculum of rat combined hippocampal-entorhinal cortex slices. In bursting cells we found a significantly higher resting membrane potential than in regular firing cells. Upon hyperpolarization both cell types expressed a delayed inward rectification with a subsequent afterdepolarization. While in regular firing cells longer lasting depolarizing current injection caused a train of action potentials with a rather marked decline of discharge frequency, bursting cells displayed only little frequency accommodation. Regular firing cells-usually displayed a fast and a slow afterhyperpolarization following a train of action potentials, while bursting neurons present only a slow afterhyperpolarization. Copyright (C) 1996 Elsevier Science Ireland Ltd.
引用
收藏
页码:41 / 44
页数:4
相关论文
共 18 条
[1]  
Amaral D G, 1991, Hippocampus, V1, P415, DOI 10.1002/hipo.450010410
[2]   Low Mg2+ induced epileptiform activity in the subiculum before and after disconnection from rat hippocampal and entorhinal cortex slices [J].
Behr, J ;
Heinemann, U .
NEUROSCIENCE LETTERS, 1996, 205 (01) :25-28
[3]   ELECTRO-PHYSIOLOGICAL PROPERTIES OF NEOCORTICAL NEURONS INVITRO [J].
CONNORS, BW ;
GUTNICK, MJ ;
PRINCE, DA .
JOURNAL OF NEUROPHYSIOLOGY, 1982, 48 (06) :1302-1320
[4]   DEMONSTRATION OF CAUDALLY DIRECTED HIPPOCAMPAL EFFERENTS IN THE RAT BY INTRACELLULAR INJECTION OF HORSERADISH-PEROXIDASE [J].
FINCH, DM ;
BABB, TL .
BRAIN RESEARCH, 1981, 214 (02) :405-410
[5]   ENDOGENOUS NATURE OF SPONTANEOUS BURSTING IN HIPPOCAMPAL PYRAMIDAL NEURONS [J].
HABLITZ, JJ ;
JOHNSTON, D .
CELLULAR AND MOLECULAR NEUROBIOLOGY, 1981, 1 (04) :325-334
[6]   ELECTROPHYSIOLOGY AND BURST-FIRING OF RAT SUBICULAR PYRAMIDAL NEURONS INVITRO - A COMPARISON WITH AREA CA1 [J].
MASON, A .
BRAIN RESEARCH, 1993, 600 (01) :174-178
[7]   VARIATIONS IN ELECTRO-PHYSIOLOGICAL PROPERTIES OF HIPPOCAMPAL-NEURONS IN DIFFERENT SUBFIELDS [J].
MASUKAWA, LM ;
BENARDO, LS ;
PRINCE, DA .
BRAIN RESEARCH, 1982, 242 (02) :341-344
[8]   MEMBRANE-PROPERTIES OF RAT SUBICULAR NEURONS IN-VITRO [J].
MATTIA, D ;
HWA, GGC ;
AVOLI, M .
JOURNAL OF NEUROPHYSIOLOGY, 1993, 70 (03) :1244-1248
[9]   COMPARATIVE ELECTROPHYSIOLOGY OF PYRAMIDAL AND SPARSELY SPINY STELLATE NEURONS OF THE NEOCORTEX [J].
MCCORMICK, DA ;
CONNORS, BW ;
LIGHTHALL, JW ;
PRINCE, DA .
JOURNAL OF NEUROPHYSIOLOGY, 1985, 54 (04) :782-806
[10]   CHARACTERISTICS OF CA1 NEURONS RECORDED INTRACELLULARLY IN HIPPOCAMPAL INVITRO SLICE PREPARATION [J].
SCHWARTZKROIN, PA .
BRAIN RESEARCH, 1975, 85 (03) :423-436