Characterization of cytolethal distending toxin genes and expression in Shiga toxin-producing Escherichia coli strains of non-O157 serogroups

被引：95

作者：

Bielaszewska, M

Fell, M

Greune, L

Prager, R

Fruth, A

Tschäpe, H

Schmidt, MA

Karch, H

机构：

[1] Univ Klinikum Munster, Inst Hyg, D-48149 Munster, Germany

[2] Univ Munster, Inst Infektol, ZMBE, D-48149 Munster, Germany

[3] Robert Koch Inst, D-38855 Wernigerode, Germany

来源：

INFECTION AND IMMUNITY | 2004年 / 72卷 / 03期

关键词：

D O I：

10.1128/IAI.72.3.1812-1816.2004

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We identified cytolethal distending toxin and its gene (cdt) in 17 of 340 non-O157 Shiga toxin-producing Eschetichia coli (STEC) strains (serotypes O73:H18,O91:H21, O113:H21, and O153:H18), all of which were eae negative. cdt is either chromosomal and homologous to cdt-V (serotypes O73:H18, O91021, and O113:R21) or plasmidborne and identical to cdt-III (serotype O153:H18). Among eae-negative STEC, cdt was associated with disease (P = 0.003).

引用

页码：1812 / 1816

页数：5

共 24 条

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