10′-hydroxyusambarensine, a new antimalarial bisindole alkaloid from the roots of Strychnos usambarensis

被引：30

作者：

Frédérich, M

Tits, M

Hayette, MP

Brandt, V

Penelle, J

DeMol, P

Llabrès, G

Angenot, L

机构：

[1] Univ Liege, Inst Pharm, Lab Pharmacognosy, CHU, B-4000 Liege, Belgium

[2] Univ Liege, Lab Med Microbiol, CHU, B-4000 Liege, Belgium

[3] Inst Phys, Lab NMR, B-4000 Liege, Belgium

来源：

JOURNAL OF NATURAL PRODUCTS | 1999年 / 62卷 / 04期

关键词：

D O I：

10.1021/np980375m

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Reinvestigation of Strychnos usambarensis Gilg resulted in the isolation of a tertiary phenolic bisindole alkaloid, 10'-hydroxyusambarensine (1), which was identified by detailed spectroscopic methods. Compound 1 was moderately active against two strains of Plasmodium falciparum in vitro.

引用

页码：619 / 621

页数：3

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