Does the presentation of Creutzfeldt-Jakob disease vary by age or presumed etiology? A meta analysis of the past 10 years

被引：42

作者：

Appleby, Brian S.

Appleby, Kristin K.

Rabins, Peter V.

机构：

[1] Johns Hopkins Univ Hosp, Baltimore, MD 21287 USA

[2] Georgetown Univ Hosp, Washington, DC 20007 USA

来源：

JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES | 2007年 / 19卷 / 04期

关键词：

D O I：

10.1176/appi.neuropsych.19.4.428

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

It is not clear whether differences in symptom presentation vary by age or etiological subtype in Creutzfeldt-Jakob disease. A PubMed search was conducted using the keyword "Creutzfeldt-Jakob" and results within the last 10 years were sorted by the English language. We found that certain characteristics, such as affective illness (28.8%), present more commonly in younger patients irrespective of disease type. Young age of onset predicts presenting symptoms of affective illness, sleep disturbance, and poor concentration, as well as certain neurological symptoms, including cerebellar/gait disturbance, visual/oculomotor disturbance, sensory disorder, vertigo/dizziness, and headache.

引用

页码：428 / 435

页数：8

共 9 条

[1] Clinical course in young patients with sporadic Creutzfeldt-Jakob disease [J].

Boesenberg, C ;

Schulz-Schaeffer, WJ ;

Meissner, B ;

Kallenberg, K ;

Bartl, M ;

Heinemann, U ;

Krasnianski, A ;

Stoeck, K ;

Varges, D ;

Windl, O ;

Kretzschmar, HA ;

Zerr, I .

ANNALS OF NEUROLOGY, 2005, 58 (04) :533-543

[2] CREUTZFELDT-JAKOB DISEASE IN FRANCE .2. CLINICAL CHARACTERISTICS OF 124 CONSECUTIVE VERIFIED CASES DURING THE DECADE 1968-1977 [J].

BROWN, P ;

CATHALA, F ;

SADOWSKY, D ;

GAJDUSEK, DC .

ANNALS OF NEUROLOGY, 1979, 6 (05) :430-437

[3] Determinants of diagnostic investigation sensitivities across the clinical spectrum of sporadic Creutzfeldt-Jakob disease [J].

Collins, S. J. ;

Sanchez-Juan, P. ;

Masters, C. L. ;

Klug, G. M. ;

van Duijn, C. ;

Poleggi, A. ;

Pocchiari, M. ;

Almonti, S. ;

Cuadrado-Corrales, N. ;

de Pedro-Cuesta, J. ;

Budka, H. ;

Gelpi, E. ;

Glatzel, M. ;

Tolnay, M. ;

Hewer, E. ;

Zerr, I. ;

Heinemann, U. ;

Kretszchmar, H. A. ;

Jansen, G. H. ;

Olsen, E. ;

Mitrova, E. ;

Alperovitch, A. ;

Brandel, J. -P. ;

Mackenzie, J. ;

Murray, K. ;

Will, R. G. .

BRAIN, 2006, 129 :2278-2287

[4] Hereditary Creutzfeldt-Jakob disease and fatal familial insomnia [J].

Gambetti, P ;

Parchi, P ;

Chen, SG .

CLINICS IN LABORATORY MEDICINE, 2003, 23 (01) :43-+

[5] Molecular classification of sporadic Creutzfeldt-Jakob disease [J].

Hill, AF ;

Joiner, S ;

Wadsworth, JDF ;

Sidle, KCL ;

Bell, JE ;

Budka, H ;

Ironside, JW ;

Collinge, J .

BRAIN, 2003, 126 :1333-1346

[6] Psychiatric manifestations of Creutzfeldt Jakob disease: A 25-year analysis [J].

Wall, CA ;

Rummans, TA ;

Aksamit, AJ ;

Krahn, LE ;

Pankratz, VS .

JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES, 2005, 17 (04) :489-495

[7] A RETROSPECTIVE STUDY OF CREUTZFELDT-JAKOB DISEASE IN ENGLAND AND WALES 1970-79 .1. CLINICAL-FEATURES [J].

WILL, RG ;

MATTHEWS, WB .

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 1984, 47 (02) :134-140

[8] New variant Crutzfeldt-Jakob disease: psychiatric features [J].

Zeidler, M ;

Johnstone, EC ;

Bamber, RWK ;

Dickens, CM ;

Fisher, CJ ;

Francis, AF ;

Goldbeck, R ;

Higgo, R ;

JohnsonSabine, EC ;

Lodge, GJ ;

McGarry, P ;

Mitchell, S ;

Tarlo, L ;

Turner, M ;

Ryley, P ;

Will, RG .

LANCET, 1997, 350 (9082) :908-910

[9]

Zerr I., 1997, Journal of the Neurological Sciences, V150, pS191, DOI 10.1016/S0022-510X(97)85804-2

← 1 →