Organic modified mesoporous MCM-41 through solvothermal process as drug delivery system

被引：133

作者：

Zeng, W

Qian, XF ^{[1
]}

Zhang, YB

Yin, J

Zhu, ZK

机构：

[1] Shanghai Jiao Tong Univ, Sch Chem & Chem Technol, State Key Lab Composite Mat, Shanghai 200240, Peoples R China

[2] Tianjin Univ Sci & Technol, Coll Mat Sci & Chem Engn, Tianjin 300222, Peoples R China

来源：

MATERIALS RESEARCH BULLETIN | 2005年 / 40卷 / 05期

关键词：

mesoporous materials; surfaces; sol-gel chemistry; X-ray diffraction; diffusion;

D O I：

10.1016/j.materresbull.2005.02.011

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

MCM-41 materials modified by organic aminopropyl groups have been successfully prepared through solvothermal process and have been used as drug-controlled delivery system of aspirin. The results show that the releasing properties of this delivery system are affected by the amount of aminopropyl groups on the pore wall and the ordered structure of mesoporous materials. These materials were characterized by XRD, TG, FT-IR, TEM, UV and N-2 adsorption. (c) 2005 Elsevier Ltd. All rights reserved.

引用

页码：766 / 772

页数：7

共 14 条

[1] A NEW FAMILY OF MESOPOROUS MOLECULAR-SIEVES PREPARED WITH LIQUID-CRYSTAL TEMPLATES [J].

BECK, JS ;

VARTULI, JC ;

ROTH, WJ ;

LEONOWICZ, ME ;

KRESGE, CT ;

SCHMITT, KD ;

CHU, CTW ;

OLSON, DH ;

SHEPPARD, EW ;

MCCULLEN, SB ;

HIGGINS, JB ;

SCHLENKER, JL .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1992, 114 (27) :10834-10843

[2] Monoglyceride synthesis by heterogeneous catalysis using MCM-41 type silicas functionalized with amino groups [J].

Cauvel, A ;

Renard, G ;

Brunel, D .

JOURNAL OF ORGANIC CHEMISTRY, 1997, 62 (03) :749-751

[3] Functionalized monolayers on ordered mesoporous supports [J].

Feng, X ;

Fryxell, GE ;

Wang, LQ ;

Kim, AY ;

Liu, J ;

Kemner, KM .

SCIENCE, 1997, 276 (5314) :923-926

[4] Selective adsorbents from ordered mesoporous silica [J].

Ho, KY ;

McKay, G ;

Yeung, KL .

LANGMUIR, 2003, 19 (07) :3019-3024

[5] Tailoring surface and structural properties of MCM-41 silicas by bonding organosilanes [J].

Jaroniec, CP ;

Kruk, M ;

Jaroniec, M ;

Sayari, A .

JOURNAL OF PHYSICAL CHEMISTRY B, 1998, 102 (28) :5503-5510

[6]

JARONIEC M, 2003, MESOPOR MOL SIEVES, V117, P325

[7] ORDERED MESOPOROUS MOLECULAR-SIEVES SYNTHESIZED BY A LIQUID-CRYSTAL TEMPLATE MECHANISM [J].

KRESGE, CT ;

LEONOWICZ, ME ;

ROTH, WJ ;

VARTULI, JC ;

BECK, JS .

NATURE, 1992, 359 (6397) :710-712

[8] A mesoporous silica nanosphere-based carrier system with chemically removable CdS nanoparticle caps for stimuli-responsive controlled release of neurotransmitters and drug molecules [J].

Lai, CY ;

Trewyn, BG ;

Jeftinija, DM ;

Jeftinija, K ;

Xu, S ;

Jeftinija, S ;

Lin, VSY .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2003, 125 (15) :4451-4459

[9] Toward a better control of internal structure and external morphology of mesoporous silicas synthesized using a nonionic surfactant [J].

Léonard, A ;

Blin, JL ;

Robert, M ;

Jacobs, PA ;

Cheetham, AK ;

Su, BL .

LANGMUIR, 2003, 19 (13) :5484-5490

[10] Photo-switched storage and release of guest molecules in the pore void of coumarin-modified MCM-41 [J].

Mal, NK ;

Fujiwara, M ;

Tanaka, Y ;

Taguchi, T ;

Matsukata, M .

CHEMISTRY OF MATERIALS, 2003, 15 (17) :3385-3394

← 1 2 →