Ribozymes: The hammerhead swings into action

被引：10

作者：

Doudna, JA ^{[1
]}

机构：

[1] Yale Univ, Dept Mol Biophys & Biochem, New Haven, CT 06520 USA

[2] Yale Univ, Howard Hughes Med Inst, New Haven, CT 06520 USA

来源：

CURRENT BIOLOGY | 1998年 / 8卷 / 14期

关键词：

D O I：

10.1016/S0960-9822(98)70316-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A new crystal structure of a modified hammerhead ribozyme reveals an intermediate conformation that may explain discrepancies between previous structures and the required orientation of the labile bond in the ribozyme's active site.

引用

页码：R495 / R497

页数：3

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