In vivo proton magnetic resonance spectroscopy of the medial temporal lobes of former prisoners of war with and without posttraumatic stress disorder

被引：27

作者：

Brown, S

Freeman, T

Kimbrell, T

Cardwell, D

Komoroski, R

机构：

[1] Cent Arkansas Vet Healthcare Syst, Mental Hlth Serv, Little Rock, AR USA

[2] Univ Arkansas, S Cent Mental Illness REs, Little Rock, AR 72204 USA

[3] Univ Arkansas, Ctr Clin, MIRECC, Little Rock, AR 72204 USA

[4] Univ Arkansas, Dept Psychiat, Little Rock, AR 72204 USA

[5] Univ Arkansas, Dept Radiol, Little Rock, AR 72204 USA

[6] Univ Arkansas, Dept Pathol, Little Rock, AR 72204 USA

[7] Univ Arkansas, Dept Biochem, Little Rock, AR 72204 USA

来源：

JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES | 2003年 / 15卷 / 03期

关键词：

D O I：

10.1176/appi.neuropsych.15.3.367

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Proton magnetic resonance spectroscopy was used to compare medial temporal lobe (MTL) concentrations of N-acetylaspartate and choline between former prisoners of war (POWS) with and without posttraumatic stress disorder (PTSD). MTL N-acetylaspartate and reexperiencing symptoms correlated strongly in the POW subjects with PTSD, suggesting a relationship between reexperiencing symptoms and the integrity of MTL structures.

引用

页码：367 / 370

页数：4

共 14 条

[1]

Bremner JD, 1997, ARCH GEN PSYCHIAT, V54, P246

[2]

BREMNER JD, 1995, AM J PSYCHIAT, V152, P973

[3] Does stress damage the brain? [J].