Bone loss in thyroid disease - Role of low TSH and high thyroid hormone

被引:27
作者
Abe, Etsuko [1 ,2 ]
Sun, Li [1 ,2 ]
Mechanick, Jeffrey [1 ,2 ]
Iqbal, Jameel [1 ,2 ]
Yamoah, Kosj [1 ,2 ]
Baliram, Ramkumarie [1 ,2 ]
Arabi, Ario [1 ,2 ]
Moonga, Baljit S. [1 ,2 ]
Davies, Terry E. [1 ,2 ]
Zaidi, Mone [1 ,2 ]
机构
[1] Mt Sinai Sch Med, James Peters Vet Affairs Med Ctr, Mt Sinai Bone Program, New York, NY 10029 USA
[2] Mt Sinai Sch Med, James Peters Vet Affairs Med Ctr, Thyroid Res Unit, New York, NY 10029 USA
来源
SKELETAL BIOLOGY AND MEDICINE, PT A: ASPECTS OF BONE MORPHOGENESIS AND REMODELING | 2007年 / 1116卷
关键词
thyroid receptor; osteoporosis; bone remodeling;
D O I
10.1196/annals.1402.062
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
More than 10% of postmenopausal women in the United States receive thyroid hormone replacement therapy and up to 20% of these women are over-replaced inducing subclinical hyperthyroidism. Because hyperthyroidism and post menopausal osteoporosis overlap in women of advancing age, it is urgent to understand the effect of thyroid hormone excess on bone. We can now provide results that not thyroid hormones but also TSH itself has an equally important role to play in bone remodeling.
引用
收藏
页码:383 / 391
页数:9
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