Cloning and sequence analysis of the human salivary peroxidase-encoding cDNA

被引：20

作者：

Kiser, C

Caterina, J

Engler, JA

Rahemtulla, B

Rahemtulla, F

机构：

[1] UNIV ALABAMA,SCH MED,DEPT BIOCHEM & MOL GENET,BIRMINGHAM,AL 35294

[2] UNIV ALABAMA,SCH MED,DEPT PEDIAT DENT,BIRMINGHAM,AL 35294

[3] UNIV ALABAMA,SCH MED,DEPT ORAL BIOL,BIRMINGHAM,AL 35294

[4] UNIV ALABAMA,SCH MED,ORAL BIOL RES CTR,BIRMINGHAM,AL 35294

[5] UNIV ALABAMA,SCH DENT,DEPT PEDIAT DENT,BIRMINGHAM,AL 35294

[6] UNIV ALABAMA,SCH DENT,DEPT ORAL BIOL,BIRMINGHAM,AL 35294

[7] UNIV ALABAMA,SCH DENT,DEPT BIOCHEM & MOL GENET,BIRMINGHAM,AL 35294

来源：

GENE | 1996年 / 173卷 / 02期

关键词：

salivary gland; saliva; lactoperoxidase; in vitro transcription and translation;

D O I：

10.1016/0378-1119(96)00078-9

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

A cDNA (hSPO) encoding human salivary peroxidase (hSPO) was isolated and its nucleotide (nt) sequence determined. The coding sequence resembles those of other mammalian peroxidases and contains a 3' untranslated region of 538 nt, In a rabbit reticulocyte lysate transcription/translation system, the cDNA produces a major protein product of approx, 67 kDa, which corresponds to the calculated molecular weight of unglycosylated hSPO.

引用

页码：261 / 264

页数：4

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