Lethal infection of C3H/HeJ and C3H/SCID mice with an isolate of Leptospira interrogans serovar Copenhageni

被引：49

作者：

Nally, JE

Fishbein, MC

Blanco, DR

Lovett, MA

机构：

[1] Univ Calif Los Angeles, Dept Med, Div Infect Dis, Los Angeles, CA 90095 USA

[2] Univ Calif Los Angeles, Dept Pathol & Lab Med, Los Angeles, CA 90095 USA

来源：

INFECTION AND IMMUNITY | 2005年 / 73卷 / 10期

关键词：

D O I：

10.1128/IAI.73.10.7014-7017.2005

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Leptospira interrogans serovar Copenhageni strain RJ16441, a blood isolate from humans with the severe pulmonary form of leptospirosis, has previously been shown to cause fatal pulmonary hemorrhage in guinea pigs and asymptomatic chronic renal tubular colonization with urinary shedding in rats. In this study, RJ16441 caused lethal infection of both C3H/HeJ and C3H/SCID mice, but no hemorrhagic phenomena were observed.

引用

页码：7014 / 7017

页数：4

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