Recombination between the drfA12-orfF-aadA2 cassette array and an aadA1 gene cassette creates a hybrid cassette, aadA8b

被引:27
作者
Gestal, AM
Stokes, HW
Partridge, SR
Hall, RM
机构
[1] Univ Sydney, Sch Mol & Microbial Biosci, Sydney, NSW 2006, Australia
[2] Macquarie Univ, Dept Chem & Biomol Sci, N Ryde, NSW 2109, Australia
关键词
D O I
10.1128/AAC.49.11.4771-4774.2005
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Homologous recombination between closely related gene cassettes, such as aadA1 and aadA2, which are 89% identical, can create hybrid cassettes and hybrids of existing cassette arrays. A new cassette array, dfrA12-orfF-aadA8b, which was created by such a recombination event occurring within the aadA2 cassette in the dfrA12-orfF-aadA2 array, has been identified.
引用
收藏
页码:4771 / 4774
页数:4
相关论文
共 16 条
[1]   REVISED ANALYSIS OF AADA2 GENE OF PLASMID PSA [J].
BITO, A ;
SUSANI, M .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1994, 38 (05) :1172-1175
[2]   Evolution of antibiotic resistance in Salmonella enterica serovar typhimurium strains isolated in the Czech Republic between 1984 and 2002 [J].
Faldynova, M ;
Pravcova, M ;
Sisak, F ;
Havlickova, H ;
Kolackova, I ;
Cizek, A ;
Karpiskova, R ;
Rychlik, I .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2003, 47 (06) :2002-2005
[3]   Antibiotic resistance in gram-negative bacteria: the role of gene cassettes and integrons [J].
Hall, RM ;
Collis, CM .
DRUG RESISTANCE UPDATES, 1998, 1 (02) :109-119
[4]   A NOVEL DIHYDROFOLATE-REDUCTASE CASSETTE INSERTED IN AN INTEGRON BORNE ON A TN21-LIKE ELEMENT [J].
HEIKKILA, E ;
SKURNIK, M ;
SUNDSTROM, L ;
HUOVINEN, P .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1993, 37 (06) :1297-1304
[5]   The gene cassette metagenome is a basic resource for bacterial genome evolution [J].
Holmes, AJ ;
Gillings, MR ;
Nield, BS ;
Mabbutt, BC ;
Nevalainen, KMH ;
Stokes, HW .
ENVIRONMENTAL MICROBIOLOGY, 2003, 5 (05) :383-394
[6]   Detection of mutations in the gyrA gene and class I integron from quinolone-resistant Salmonella enterica serovar Choleraesuis isolates in Taiwan [J].
Huang, TM ;
Chang, YF ;
Chang, CF .
VETERINARY MICROBIOLOGY, 2004, 100 (3-4) :247-254
[7]   Transposon Tn21, flagship of the floating genome [J].
Liebert, CA ;
Hall, RM ;
Summers, AO .
MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS, 1999, 63 (03) :507-+
[8]   Detection and characterization of class 1 integrons in enterohemorrhagic Escherichia coli [J].
Morabito, S ;
Tozzoli, R ;
Caprioli, A ;
Karch, H ;
Carattoli, A .
MICROBIAL DRUG RESISTANCE, 2002, 8 (02) :85-91
[9]   Complex multiple antibiotic and mercury resistance region derived from the r-det of NR1 (R100) [J].
Partridge, SR ;
Hall, RM .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2004, 48 (11) :4250-4255
[10]   In34, a complex In5 family class 1 integron containing orf513 and dfrA10 [J].
Partridge, SR ;
Hall, RM .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2003, 47 (01) :342-349